diff --git a/src/core/directives/link.ts b/src/core/directives/link.ts
index daac1bc79..ca6eeca1d 100644
--- a/src/core/directives/link.ts
+++ b/src/core/directives/link.ts
@@ -44,7 +44,7 @@ export class CoreLinkDirective implements OnInit {
     @Input() autoLogin: boolean | string = true; // Whether to try to use auto-login. Values yes/no/check are deprecated.
     @Input() showBrowserWarning = true; // Whether to show a warning before opening browser. Defaults to true.
 
-    protected element: HTMLElement;
+    protected element: HTMLElement | HTMLIonFabButtonElement | HTMLIonButtonElement | HTMLIonItemElement;
 
     constructor(
         element: ElementRef,
@@ -54,10 +54,18 @@ export class CoreLinkDirective implements OnInit {
     }
 
     /**
-     * Function executed when the component is initialized.
+     * @inheritdoc
      */
-    ngOnInit(): void {
-        CoreDom.initializeClickableElementA11y(this.element, (event) => this.performAction(event));
+    async ngOnInit(): Promise<void> {
+        let hasNativeButton = false;
+        if ('componentOnReady' in this.element) {
+            await this.element.componentOnReady();
+
+            // Native buttons may be already accessible and does not neet to set TabIndex and role.
+            hasNativeButton = !!this.element.shadowRoot?.querySelector('.button-native');
+        }
+
+        CoreDom.initializeClickableElementA11y(this.element, (event) => this.performAction(event), !hasNativeButton);
     }
 
     /**
@@ -79,7 +87,7 @@ export class CoreLinkDirective implements OnInit {
 
         href = href || this.element.getAttribute('href') || this.element.getAttribute('xlink:href');
 
-        if (!href || CoreUrlUtils.getUrlScheme(href) == 'javascript') {
+        if (!href || CoreUrlUtils.getUrlScheme(href) === 'javascript') {
             return;
         }
 
diff --git a/src/core/features/course/components/course-format/course-format.html b/src/core/features/course/components/course-format/course-format.html
index 8a837aa6a..423cf7031 100644
--- a/src/core/features/course/components/course-format/course-format.html
+++ b/src/core/features/course/components/course-format/course-format.html
@@ -54,12 +54,10 @@
     <ion-fab-button size="small" *ngIf="communicationRoomUrl" [href]="communicationRoomUrl" core-link capture="false"
         [attr.aria-label]="'core.course.communicationroomlink' | translate">
         <ion-icon name="far-comments" aria-hidden="true" />
-        <span class="sr-only">{{'core.course.communicationroomlink' | translate }}</span>
     </ion-fab-button>
     <ion-fab-button *ngIf="displayCourseIndex" (click)="openCourseIndex()" [userTour]="courseIndexTour"
         [attr.aria-label]="'core.course.courseindex' | translate" color="secondary">
         <ion-icon name="fas-list-ul" aria-hidden="true" />
-        <span class="sr-only">{{'core.course.courseindex' | translate }}</span>
     </ion-fab-button>
 </ion-fab>
 
diff --git a/src/core/singletons/dom.ts b/src/core/singletons/dom.ts
index e67b78ba4..367418436 100644
--- a/src/core/singletons/dom.ts
+++ b/src/core/singletons/dom.ts
@@ -537,10 +537,12 @@ export class CoreDom {
      *
      * @param element Element to listen to events.
      * @param callback Callback to call when clicked or the key is pressed.
+     * @param setTabIndex Whether to set tabindex and role.
      */
     static initializeClickableElementA11y(
         element: HTMLElement & {disabled?: boolean},
         callback: (event: MouseEvent | KeyboardEvent) => void,
+        setTabIndex = true,
     ): void {
         const enabled = () => !CoreUtils.isTrueOrOne(element.dataset.disabledA11yClicks ?? 'false');
 
@@ -563,14 +565,14 @@ export class CoreDom {
             }
 
             if (event.key === ' ' || event.key === 'Enter') {
+                callback(event);
+
                 event.preventDefault();
                 event.stopPropagation();
-
-                callback(event);
             }
         });
 
-        if (element.tagName !== 'BUTTON' && element.tagName !== 'A') {
+        if (setTabIndex && element.tagName !== 'BUTTON' && element.tagName !== 'A') {
             // Set tabindex if not previously set.
             if (element.getAttribute('tabindex') === null) {
                 element.setAttribute('tabindex', element.disabled ? '-1' : '0');